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Tesamorelin is a GHRH analog prescribed for its body composition effects, specifically reduction of visceral adiposity and improvement in growth hormone pulse amplitude
Wouldnt be without them when summer comes or if Im using Sunbeds getting ready for a holiday
Traditionally GLP-1(9-36) was considered inactive, however more recent studies indicate that GLP-1(9-36) can contribute to inhibiting glucagon secretion by inhibiting voltage-gated calcium channels through a GPCR mechanism, an effect which reduces the number of glucagon containing vesicles that are available for exocytosis, thereby contributing the the decrease in glucagon secretion (Figure 1)(Zheng et al, 2024)
This produces a strong anabolic bone-building response while causing less bone resorption and less hypercalcemia compared to teriparatide
